000			02886cam a2200325 a 4500
001			16942854
003			OSt
005			20150408114145.0
008			110830s2012 paua b 001 0 eng
010			_a 2011036549
020			_a9781609138998 (hardback : alk. paper)
035			_a(DNLM)101568248
040			_aDNLM/DLC _cDLC _dDLC
042			_apcc
050	0	0	_aRC683.5.E94 _bW37 2011
060	1	0	_aWG 141.5.F9
082	0	0	_a616.120754 _223 _bPRE
245	0	0	_aPrinciples of exercise testing and interpretation : _bincluding pathophysiology and clinical applications / _cKarlman Wasserman ... [et al.].
250			_a5th ed.
260			_aPhiladelphia : _bWolters Kluwer Health/Lippincott Williams & Wilkins, _cc2012.
300			_axiii, 572 p. : _bcol. ill. ; _c29 cm.
504			_aIncludes bibliographical references and index.
520			_a"In this fifth edition of Principles of Exercise Testing and Interpretation, as in earlier editions, we attempt to develop conceptual advances in the physiology and pathophysiology of exercise, particularly as related to the practice of medicine. The underlying theme of the book continues to be the recognition that the most important requirement for exercise performance is transport of oxygen to support the bioenergetic processes in the muscle cells (including, of course, the heart) and elimination of the carbon dioxide formed as a byproduct of exercise metabolism. Thus, appropriate cardiovascular and ven- tilatory responses are required to match those of muscle respiration in meeting the energy demands of exercise. As depicted by the logo on the book cover, normal exercise performance requires an efficient coupling of external to internal (cellular) respiration. Appropriate treatment of exercise intolerance requires that patients' symptoms be thought of in terms of a gas exchange defect between the cell and the environment. The defect may be in the lungs, heart, peripheral or pulmonary circulations, the muscles themselves, or there may be a combination of defects. Thus, we describe the pathophysiology in gas transport and exchange that affect any site in the cardio- respiratory coupling between the lungs and the muscles. We illustrate how cardiopulmonary exercise testing can provide the means for a critical evaluation by the clinician-scientist of the functional competency of each component in the coupling of cellular to external respiration, including the cardiovascular system. To achieve this, clinical cases are used to illustrate the wide spectrum of pathophysiology capable of causing exercise intolerance"--Provided by publisher.
650	1	2	_aExercise Test. _98989
650	2	2	_aPhysical Exertion _xphysiology. _938383
700	1		_aWasserman, Karlman. _938384
906			_a7 _bcbc _corignew _d1 _eecip _f20 _gy-gencatlg
942			_2ddc _cBOOK
999			_c31503 _d266003