Includes bibliographical references and index.

1. Molecular evolution / Sylvia Nagl -- 2. Gene finding / John G. Sgouros and Richard M. Twyman -- 3. Sequence comparison methods / Christine Orengo -- 4. Amino acid residue conservation / William S.J. Valdar and David T. Jones -- 5. Function prediction from protein sequence / Sylvia B. Nagl -- 6. Protein structure comparison / Ian Sillitoe and Christine Orengo -- 7. Protein structure classifications / Frances Pearl and Christine Orengo -- 8. Comparative modeling / Andrew C.R. Martin -- 9. Protein structure prediction / David T. Jones -- 10. From protein structure to function / Annabel E. Todd --11. From structure-based genome annotation to understanding genes and proteins / Sarah A. Teichmann -- 12. Global approaches for studying protein-protein interactions / Sarah A. Teichmann -- 13. Predicting the structure of protein-biomolecular interactions / Richard M. Jackson -- 14. Experimental use of DNA arrays / Paul Kellam and Xiaohui Liu -- 15. Mining gene expression data / Xiaohui Liu and Paul Kellam -- 16. Proteomics / Malcolm P. Weir, Walter P. Blackstock and Richard M. Twyman -- 17. Data managament [sic] of biological information / Nigel J. Martin -- 18. Internet technologies for bioinformatics / Andrew C.R. Martin -- Glossary -- Index.