Includes bibliographical references and index.

Merging mathematical and physiological knowledge : dimensions and challenges -- Mathematical modeling of physiological systems -- Parameter selection methods in inverse problem formulation -- Application of the unscented Kalman filtering to parameter estimation -- Integrative and reductionist approaches to modeling of control of breathing -- Parameter identification in a respiratory control system model with delay -- Experimental studies of respiration and apnea -- Model validation and control issues in the respiratory system -- Experimental studies of the baroreflex -- Development of patient specific cardiovascular models predicting dynamics in response to orthostatic stress challenges -- Parameter estimation of a model for baroreflex control of unstressed volume.