Includes bibliographical references and index.

Immunotoxicology testing: past and future / Michael I. Luster, G. Frank Gerberick -- Developmental immunotoxicity (DIT): the why, when, and how of DIT testing / Rodney R. Dietert, Jamie DeWitt -- An In vivo tiered approach to test immunosensitization by low molecular weight compounds / Irene S. Ludwig, Lydia M. Kwast, Daniëlle Fiechter, Raymond H. Pieters -- Risk of autoimmune disease: challenges for immunotoxicity testing / Rodney R. Dietert, Janice M. Dietert, Jerrie Gavalchin -- Markers of inflammation / Dori R. Germolec, Rachel P. Frawley, Ellen Evans -- Evaluating macrophages in immunotoxicity testing / John B. Barnett, Kathleen M. Brundage -- Host resistance assays including bacterial challenge models / Florence G. Burleson, Gary R. Burleson -- Viral host resistance studies / Wendy Jo Freebern -- Parasite challenge as host resistance models for immunotoxicity testing / Robert W. Luebke -- Tumor challenges in immunotoxicity testing / Sheung Ng, Kotaro Yoshida, Judith T. Zelikoff -- The T-dependent antibody response to keyhole limpet hemocyanin in Rodents / Lisa M. Plitnick, Danuta J. Herzyk -- The Sheep erythrocyte T-dependent antibody response (TDAR) / Kimber L. White, Deborah L. Musgrove, Ronnetta D. Brown -- The Delayed type hypersensitivity assay using protein and xenogeneic cell antigens / Rodney R. Dietert, Terry L. Bunn, Ji-Eun Lee -- The Cytotoxic T lymphocyte assay for evaluating cell-mediated immune function / Gary R. Burleson, Florence G. Burleson, Rodney R. Dietert -- NK cell assays in immunotoxicity testing / Qing Li --

The Local lymph node assay and skin sensitization testing / Ian Kimber, Rebecca J. Dearman -- Use of contact hypersensitivity in immunotoxicity testing / Jacques Descotes -- Evaluation of apoptosis in immunotoxicity testing / Mitzi Nagarkatti, Sadiye Amcaoglu Rieder, Dilip Vakharia, Prakash S. Nagarkatti -- Dendritic cells in immunotoxicity testing / Donghong Gao, David A. Lawrence -- Evaluating cytokines in immunotoxicity testing / Emanuela Corsini, Robert V. House -- Flow cytometry in preclinical drug development / Patrick B. Lappin -- Enhanced histopathology evaluation of lymphoid organs / Susan A. Elmore -- Immunotoxicity testing in nonhuman primates / Stephanie Grote-Wessels, Werner Frings, Clifford A. Smith, Gerhard F. Weinbauer -- Fundamentals of clinical immunotoxicology / Robert V. House -- In vivo functional tests for assessing immunotoxicity in birds / Keith A. Grasman -- In vitro testing for direct immunotoxicity: state of the art / D. P. Lankveld, H. Loveren, K. A. Baken, R. J. Vandebriel

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