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  <titleInfo>
    <title>RNA therapeutics</title>
    <subTitle>function, design, and delivery</subTitle>
  </titleInfo>
  <name type="personal">
    <namePart>Sioud, Mouldy.</namePart>
  </name>
  <typeOfResource>text</typeOfResource>
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    <place>
      <placeTerm type="text">New York</placeTerm>
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    <publisher>Humana Press</publisher>
    <dateIssued>c2010</dateIssued>
    <dateIssued encoding="marc">2010</dateIssued>
    <issuance>monographic</issuance>
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  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
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  <physicalDescription>
    <form authority="marcform">print</form>
    <extent>xvi, 526 p. : ill. ; 27 cm.</extent>
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  <tableOfContents>RNA modifications : a mechanism that modulates gene expression / John Karijolich, Athena Kantartzis, and Yi-Tao Yu -- Quantitative analysis of RNA modifications / John Karijolich, Athena Kantartzis, and Yi-Tao Yu -- Advances in RNA sensing by the immune system : separation of siRNA unwanted effects from RNA interference / Mouldy Sioud -- Progress in siRNA delivery using multifunctional nanoparticles / Weiwei Gao ... [et al.] -- Optimized protocols for siRNA delivery into monocytes and dendritic cells / Anne Mobergslien and Mouldy Sioud -- Systemic delivery of synthetic siRNAs / Dag R. Sørensen and Mouldy Sioud -- What are the key targeted delivery technologies of siRNA now? / Mouldy Sioud -- Using OligoWalk to identify efficient siRNA sequences / David H. Mathews -- Jet-injections of short hairpin RNA-encoding vectors into tumor cells / Wolfgang Walther, Ulrike Stein, and Hermann Lage -- Short hairpin RNA (shRNA) : design, delivery, and assessment of gene knockdown / Chris B. Moore ... [et al.] -- Effective Pol III-expressed long hairpin RNAs targeted to multiple unique sites of HIV-1 / Sheena M. Saayman, Patrick Arbuthnot, and Marc S. Weinberg -- Functional studies on RNA-transfected cell microarrays / Christina Sæten Fjeldbo ... [et al.] -- Transfection microarrays for high-throughput phenotypic screening of genes involved in cell migration / Reiko Onuki-Nagasaki ... [et al.] -- Intron-mediated RNA interference, intronic microRNAs, and applications / Shao-Yao Ying, Chen Pu Chang, and Shi-Lung Lin -- Inhibition of the microRNA pathway in zebrafish by siRNA / Anders Fjose and Xiao-Feng Zhao -- Profiling of miRNA expression and prediction of target genes / Mouldy Sioud and Lina Cekaite -- Small RNA cloning / Seungil Ro and Wei Yan -- In situ hybridization detection of microRNAs / Rui Song, Seungil Ro, and Wei Yan -- Detection and quantitative analysis of small RNAs by PCR / Suengil Ro and Wei Yan -- In vivo reprogramming of human telomerase reverse transcriptase (hTERT) by trans-splicing ribozyme to target tumor cells / Sang-Jin Lee ... [et al.] -- Design and function of triplex hairpin ribozymes / Guillermo Aquino-Jarquin, Ramiro Rojas-Hernández, and Luis Marat Alvarez-Salas -- Catalytic M1GS RNA as an antiviral agent in animals / Yong Bai, Paul Jay Fannin Rider, and Fenyong Liu -- Using live cells to generate aptamers for cancer study / Ling Meng ... [et al.] -- Primer-free aptamer selection using a random DNA library / Weihua Pan and Gary A. Clawson -- Development of TLR7/8 small RNA antagonists / Mouldy Sioud -- Modulation of dendritic cell maturation and function by siRNA-bearing 5'-triphosphate / Mouldy Sioud -- Immunotherapy of cancer with dendritic cells loaded with tumor antigens and activated through mRNA electroporation / An M.T. Van Nuffel ... [et al.] -- Non-MHC-dependent redirected T cells against tumor cells / Hilde Almåsbak, Marianne Lundby, and Anne-Marie Rasmussen -- Overcoming self-tolerance to tumour cells / Mouldy Sioud -- Recent advances in hematopoietic stem cell transplantation and perspectives of RNAi applications / Yngvar Fløisand and Mouldy Sioud.</tableOfContents>
  <note type="statement of responsibility">edited by Mouldy Sioud.</note>
  <note>Includes bibliographical references and index.</note>
  <subject authority="lcsh">
    <topic>RNA</topic>
    <topic>Therapeutic use</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Small interfering RNA</topic>
    <topic>Therapeutic use</topic>
  </subject>
  <subject authority="lcsh">
    <topic>RNA</topic>
    <topic>Therapeutic use</topic>
    <topic>Laboratory manuals</topic>
  </subject>
  <subject authority="mesh">
    <topic>RNA Interference</topic>
  </subject>
  <subject authority="mesh">
    <topic>RNA, Small Interfering</topic>
    <topic>therapeutic use</topic>
  </subject>
  <subject authority="mesh">
    <topic>Gene Therapy</topic>
  </subject>
  <subject authority="mesh">
    <topic>Neoplasms</topic>
    <topic>therapy</topic>
  </subject>
  <classification authority="lcc">RM666.R554 R53 2010</classification>
  <classification authority="ddc" edition="22">615.31 RNT</classification>
  <classification authority="nlm">W1 ME9616J v.629 2010</classification>
  <classification authority="nlm">QU 58.7</classification>
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    <titleInfo>
      <title>RNA therapeutics</title>
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    <originInfo>
      <publisher>New York, N.Y. : Humana Press, c2010</publisher>
    </originInfo>
    <identifier type="local">(OCoLC)622054770</identifier>
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    <titleInfo>
      <title>Methods in molecular biology (Clifton, N.J.) ; v. 629</title>
    </titleInfo>
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  <relatedItem type="series">
    <titleInfo>
      <title>Springer protocols</title>
    </titleInfo>
  </relatedItem>
  <identifier type="isbn">9781607616566 (hbk. : alk. paper)</identifier>
  <identifier type="isbn">1607616564 (hbk. : alk. paper)</identifier>
  <identifier type="isbn">9781607616573 (eISBN)</identifier>
  <identifier type="isbn">1607616572 (eISBN)</identifier>
  <identifier type="lccn">2010921201</identifier>
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