02534cam a22005414a 4500 15936302 OSt 20150408114105.0 091008s2010 nyua b 001 0 eng c 2009938829 GBA994351 bnb 101539678 DNLM 015380441 Uk 9780387403137 (alk. paper) 0387403132 (alk. paper) 9780387686363 (eISBN) 0387686363 (eISBN) (OCoLC)ocn436030925 NLM NLM UKM BTCTA OHX CDX YDXCP MMU DLC pcc QR189 .H35 2010 2010 K-719 QW 805 615/.372072 23 Halloran, M. Elizabeth. 18703 Design and analysis of vaccine studies / M. Elizabeth Halloran, Ira M. Longini, Jr., Claudio J. Struchiner. New York : Springer, c2010. xviii, 387 p. : ill. ; 24 cm. Statistics for biology and health, 1431-8776 Includes bibliographical references (p. 361-379) and index. Overview of vaccine effects and study designs -- Immunology and early phase trials -- Binomial and stochastic transmission models -- R[o] and deterministic models -- Evaluating protective effects of vaccination -- Models of action and time-varying VE[s] -- Further evaluation of protective effects -- Vaccine effects on post-infection outcomes -- Household-based studies -- Analysis of households in communities -- Analysis of independent households -- Assessing indirect, total, and overall effects -- Randomization and baseline transmission -- Surrogates of protection. Vaccines Research. 18704 Vaccines Statistical methods. 18705 Epidemiology Research. 18706 Case-control method. 18707 Research Design. 11610 Vaccines. Clinical Trials as Topic. Drug Evaluation methods. 18565 Research methods. Statistics as Topic. 11606 Longini, Ira M. 18708 Struchiner, Claudio J. 18709 Statistics for biology and health, 18710 7 cbc pccadap 2 ncip 20 y-gencatlg ddc DVD 26548 261048 0 2013-03-10 0 0 615/.372072 HMD 2012-12-26 CL 00400830 CL 2013-03-10 00:00:00 BOOK ddc 0 0 2013-03-10 0 0 615/.372072 HMD 2012-12-26 CL 00400832 CL 2013-03-10 00:00:00 BOOK ddc 0 0 2013-03-10 0 0 615/.372072 HMD 2012-12-26 CL 00400831 CL 2013-03-10 00:00:00 BOOK ddc 0